IFNA1 and COVID-19: A laboratory study in rats with COVID-19 showed that the use of IFN type I inducers resulted in increased viral clearance and decreased tissue inflammation.46 Data indicate that the delay in raising the IFN levels in the host runs with a worse prognosis.11 There are no case reports on the use of IFNs in COVID-19, but there are 43 records in ClinicalTrials of studies in progress, mainly using IFNs (alpha, beta and lambda) as additional therapy.