For the remaining genes (airway fibroblasts: HOOK2 and HOXA7 (Fig. 8a and b); parenchymal fibroblasts: HOXA5, HOXA6, HOXA-AS3, RB1 and NR2F1-AS1 (Fig. 9a–e)), there was no differential gene expression between donors with and without asthma. The gene discussed is HOOK2; the disease is asthma.