TLR7 and head and neck squamous cell carcinoma: As a result, higher TLR-5 expression was associated with an increased non-statistically significant risk of mortality (HR 3.13, 95%CI 0.76–5.50; I2 0.0%, p-value for I2 = 0.657), while higher TLR-7 was associated with a statistically significant decreased risk of mortality in HNSCC patients (HR 0.51, 95%CI 0.13-0.89; I2 34.6%, p-value for I2 = 0.205) (Figure 3; Table 4).