Recently, Kylmä et al. found that higher TLR-5 immunoexpression was associated with advanced N-class (N1–N3; p = 0.008), tumour site (tonsil; p = 0.006) and advanced tumour grade (grade 3; p = 0.004) in OPSCC tissues [10]. Here, TLR5 is linked to neoplasm.