Additionally, microRNA-130a, cooperatively with microRNA-145, through the inactivation of Runt-related transcription factor 3, increases cell proliferation and tumour angiogenesis in gastric cancer [64]; since T2DM increases the risk of gastric cancer following Helicobacter pylori eradication [65], this represents another field that deserves further investigation. This evidence concerns the gene RUNX3 and type 2 diabetes mellitus.