These include the multiple death receptors induced by RT expressed on the surface of tumour cells, including FAS (also known as CD95) and tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 (TRAIL-R1 and TRAIL-R2), which can render the tumour cells more vulnerable to apoptosis [20]. The gene discussed is TNFRSF10B; the disease is neoplasm.