BCL2 and acute kidney injury: Consistent with these results, LPS-induced AKI and renal tubular cells apoptosis were ameliorated by novel potential agents, such as a pluripotent autocrine growth factor progranulin, an anion transporter uncoupling protein 2 [10], the bee venom [11], and peroxiredoxin protein DJ-1 (Parkinson disease protein 7, Park7) [12], as well as by vitamin D that suppressed p53-upregulated modulator of apoptosis (PUMA) and upregulated expression of a Bcl-2 family antiapoptotic protein [13].