Cytotoxic effects on A2780 and SKOV3 ovarian cancer cells (IC50 ranging from 84 to 100 μg/mL for extract and from 77 to 169 μM for phenols, with dieckol being the most active of all, after 24 h)Induced the apoptosis on SKOV3 cells via Akt and p38 signaling pathways. The gene discussed is AKT1; the disease is ovarian cancer.