We have also shown in the same cohort that high proportions of circulating FOXP3+CD25highCD4+ T cells, suggestedly representing regulatory T cells, at birth are positively associated with being sensitized later in childhood [17] and that infants with a high proportion of CD5+ B cells at birth and during the first month of life are at increased risk for allergy development [18,19]. The gene discussed is FOXP3; the disease is allergic disease.