While the mBD-1−/− model infected with the C. albicans GDH2346-RFP strain itself is equally effective in observing oral mucosal and systemic mucosal infections, the disadvantage of the mucosal models relative to the intravenous infection models is the absence of the ability for high throughput screening and real time quantification of infection using IVIS. Here, MBD1 is linked to infection.