Despite the protective role of lowly expressed miR-18a and overexpressed TGFBR3 in NPC cell in vitro, we have performed tumor xenografts in nude mince in vivo for further verification with the results explaining that miR-18a knockdown or TGFBR3 elevation restrains tumor growth in nude mice. Here, TGFBR3 is linked to nasopharyngeal carcinoma.