To explore the effects of miR-18a from M2 macrophages on NPC cells, miR-18a mimics- or si-TGFBR3-transfected M2 macrophages or miR-18a inhibitors- or OE-TGFBR3-transfected M2 macrophages were co-cultured with SUNE-1 or CNE2 cells in the Transwell chamber, respectively. This evidence concerns the gene TGFBR3 and nasopharyngeal carcinoma.