We defined a suspected nonalcoholic fatty liver disease case as 1 in which the individual had elevated ALT levels (≥33 U/L for men and ≥25 for women; to convert to microkatal per liter, multiply by 0.0167) in approximately 18 000 participants with clinical biochemistry data and negative HBsAg test results, finding a similar genetic estimate for elevated ALT and hospitalized nonalcoholic fatty liver disease (eMethods in the Supplement). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.