PLA2G6 and neurodegeneration with brain iron accumulation 2A: However, it was marked as relevant by our experts given that PLA2G6-associated neurodegeneration (PLAN) comprises a continuum of 3 phenotypes with overlapping clinical and radiologic features for these 2 diseases, and similar evidence can be found at Orphanet [32] that reveals that Hunter-Carpenter-McDonald syndrome has been moved to “Infantile neuroaxonal dystrophy.” In comparison of the total 13,705,230 GARD disease pairs, there are only 392 disease pairs with similarity scores greater than 0, which might direct the extension in 2 ways.