IL36B and neoplasm: Like the murine Interleukin-12 homolog M002 (Figure 1), M032 is a similarly engineered novel oncolytic Herpes Simplex Virus (HSV) mutant expressing human Interleukin-12 (13, 22, 23) and infects and kills tumor cells, releasing IL-12 within the tumor bed to elicit a potent immune-related inflammatory response.