Additionally, previous research finds that females have higher CD4+ T cell counts than age-matched males, and after in vitro stimulation females produce higher numbers of activated CD4+ T cells [44]. The greater reserve of CD4+ lymphocytes, combined with lower risk of lymphocytopenia in SARS-CoV-2 infection, may potentially decrease the risk of mortality from COVID-19 in females. The gene discussed is CD4; the disease is COVID-19.