Sugimasa H et al (Sugimasa et al., 2015) demonstrated that the NUF2 gene could be directly trans-activated by the heterogeneous ribonucleoprotein K (hnRNP K), and that the hnRNP K-NUF2 axis affected the growth of colon cancer cells by participating in processes of mitosis and proliferation. The gene discussed is NUF2; the disease is colonic neoplasm.