CD4 and intimal sarcoma: It is unknown whether wild‐type S. Typhi contains antigens able to elicit both cross‐reactive CD4+ and CD8+ T‐cell effector functions against other major invasive Salmonella for which vaccines are lacking, such as iNTS strains and PA, or how biologic differences between different invasive Salmonella strains impact T‐cell priming and the development of T‐cell memory and effector functions in humans.