KIAA0513 and Alzheimer disease: Next, we tested the differential expressions of the five hub genes in the two AD GEO datasets from the blood (data not shown; Sood et al., 2015) and found that KIAA0513 was significantly up-regulated in MCI and AD samples when compared with CN samples (P < 0.05, 0.01, 0.0001, respectively, Figure 9A).