AD samples in GSE118553 were divided into a “high-expression group” and a “low-expression group.” We acquired 17, 9, 1, 7, and 33 significant gene sets enriched in the expression groups of AP3B2, GABRD, GPR158, KIAA0513, and MAL2, respectively (Supplementary Table 4). The gene discussed is GABRD; the disease is Alzheimer disease.