As presented in Figure 2 and Table 4, hypomethylation of seven out of nine CpG sites of S100P and three out of four CpG sites of HYAL2 were significantly correlated with BC by logistic regression adjusted for age and batches of measurements (seven S100P CpG sites: ORs from 1.54 to 1.90, p < 0.03 for all; three HYAL2 CpG sites: ORs from 1.97 to 2.49, p < 0.01 for all; Table 4). This evidence concerns the gene HYAL2 and breast cancer.