MiR-101-3p transfection down-regulated the luciferase activity in KRAS 3′ UTR wt group compared with that in miR-NC and KRAS 3′ UTR wt group (Figures 7B,C), which suggested that miR-101-3p directly interacted with the 3′ UTR of KRAS mRNA in NSCLC cells. This evidence concerns the gene KRAS and non-small cell lung carcinoma.