The genes upregulated in SZ NPC included TNFRSF1B encoding TNFR2, TNFRSF10B (so called “Death Receptor” 5.5 log2), and genes for proteins that transduce TNF receptor signals, PAK1 (3.3 log 2), and PAK7 (2.2 log2; P21 protein activated kinases). This evidence concerns the gene TNFRSF1B and nasopharyngeal carcinoma.