The genes upregulated in SZ NPC included TNFRSF1B encoding TNFR2, TNFRSF10B (so called “Death Receptor” 5.5 log2), and genes for proteins that transduce TNF receptor signals, PAK1 (3.3 log 2), and PAK7 (2.2 log2; P21 protein activated kinases). The gene discussed is PAK5; the disease is nasopharyngeal carcinoma.