For example, the fusion of the ASPSCR1 and TFE3 genes could occur not only in ASPSCR1-TFE3 RCC, but also in alveolar soft part sarcoma (ASPS)23,24, a stromal tumor involving an unbalanced der (17) t(X; 17) (p11; q25) translocation. The gene discussed is ASPSCR1; the disease is renal cell carcinoma.