To enable more specific tumor targeting, our previous immunohistochemical (IHC) studies found both integrin αvβ6 and carcinoembryonic antigen cell adhesion molecule 5 (CEACAM5) to be suitable targets to identify PDAC, distinguishing tumor tissue from TAP or normal pancreatic parenchyma, and also allowing sensitive and specific metastatic lymph node detection13,14. This evidence concerns the gene CEACAM5 and neoplasm.