An MRI study about heroin addiction shows that the abnormal brain function of heroin addicts is related to ILP, the FC between left and right IPL brain regions of these untreated patients decreased significantly, these show that long-term dependence on heroin may will destroy the structure and function of IPL, besides, IPL may be the neural target for the intervention and treatment of this disease23. The gene discussed is XIAP; the disease is heroin dependence.