AR and coronary artery disorder: Similarly, the echocardiographic indices (Table 4), LVMI (β = 0.3380, p ≤ 0.001), MV E/A (β =  − 0.3751, p ≤ 0.001), PV AR (β =  − 0.3444, p ≤ 0.001) and Biplane LVEF (β = 0.3467, p = 0.010) were significantly linked with low BDNF concentration in CAD with a model fit measure r = 0.826 and r-square = 0.683.