In contrast, the CUBN rs2291521GG/ HNF1A rs55783344CC and HNF1A rs55783344CC/LIPC rs17269397AG genotype combinations were associated with a protective effect in terms of CAD risk (AOR = 0.683; 95% CI 0.518–0.899; P = 0.007 and AOR = 0.692; 95% CI 0.408–0.888; P = 0.011, respectively) (see Table 3). This evidence concerns the gene CUBN and coronary artery disorder.