In analysis of the CUBN rs2291521G > A/HNF1A rs55783344C > T/LIPC rs17269397A > G genotype combination, an association with CAD risk was identified for the combined genotype of CUBN rs2291521GA/HNF1A rs55783344CT/LIPC rs17269397AA (AOR = 2.501; 95% CI 1.382–4.527; P = 0.003). The gene discussed is CUBN; the disease is coronary artery disorder.