This includes two genes (UIMC1 and GABRG2) firstly significant at a 5% FDR and seven genes (ANK2, TBR1, PHF12, TCF7L2, SETD2, CASZ1, and NSD2), which were significant at 5% FDR previously, that firstly reach FWER significance in this larger NDD cohort (Table 2, Supplementary Data 10). The gene discussed is SETD2; the disease is Neurodevelopmental delay.