DNM1L and lung adenocarcinoma: Consistent with the results from cultured lung adenocarcinoma cells (Figs. 4 and 6), ablation of PINCH-1 from lung adenocarcinoma significantly increased the protein (Fig. 9a) and mRNA (Fig. 9b) levels of DRP1 and reduced the levels of PYCR1 (Fig. 9a) and proline (Fig. 9c) in vivo.