Tantalizingly, at least 9 different mutations of the Nna1 gene have been found in mice, and the mouse Nna1 gene is 87% homologous with the corresponding human NNA1 gene, making it plausible that NNA1 gene mutations may be involved also in certain human neurodegenerative diseases, as cited in Discussion. This evidence concerns the gene AGTPBP1 and neurodegenerative disease.