Comparing with No-DM group, DM-insulin group had a higher age, higher percentage of female, higher BMI, higher incidence of hypertension, hyperlipemia and PVD, higher incidence of prior CVA, MI and PCI, higher number of vessel diseases and left main diseases, higher EuroSCOREII, a higher ratio of on-pump CABG and longer CPB time, but a lower eGFR and LVEF, and a lower application of LIMA (Table 1). The gene discussed is INS; the disease is familial hyperlipidemia.