Smoking, T2DM, HDL-C, LDL-C, CPS, MMP-9, LOX-1, YKL-40, PAPP-A, and 10-year ICVD are significantly higher in the unstable plaque group than the stable plaque group, HDL-C is lower in the unstable plaque group than the stable plaque group (P < 0.05), see Table 1. Here, CHI3L1 is linked to type 2 diabetes mellitus.