Taking the presence or absence of unstable plaque as the dependent variable, the positive result indicators in Table 1 are the independent variables, and the results of logistic multivariate regression analysis shows that T2DM, high MMP-9, LOX-1, YKL-40 CPS, andLipids ratioare independent risk factors for unstable plaque formation (T2DM: OR = 0.399, P = 0.009; MMP-9: OR = 1.015, P = 0.000; LOX-1: OR = 1.008, P = 0.008;YKL-40: OR = 1.007, P = 0.013; CPS:OR = 1.322, P = 0.006; Lipids ratio: OR = 2.312, P = 0.001), which is shown in Table 2. Here, CHI3L1 is linked to type 2 diabetes mellitus.