The DVL3 tumours have a lower proportion of both cytotoxic CD8 + T-cells (0.187% vs. 2.05%, p = 0.01) and CD4 + T-cells (0.36% vs. 4.31%, p = 0.01) compared to the TRAMP C1 tumours (Figure 2A,B). Here, CD4 is linked to neoplasm.