MSH2 and carcinoma: Among the 33 lesions with MSH2 expression, 29 were also EPCAM-positive (25 colorectal polyps and 4 carcinomas, 2 urothelial from the urinary bladder and 2 from the endometrium), and four were noninformative EPCAM-negative (two HSIL from the cervix and two lesions from the breast) (Table 4).