Subsequently, the Bavi/b2GPI/PS complex appears to have multifunctional activities that include (i) partial masking of PS and blockage of PS receptors such as TAMs and TIMs, (ii) induction of ADCC on viable tumor vascular endothelial cells, (iii) polarization of M2 toward M1 macrophages, and (iv) maturation of DCs towards an active cross-presenting phenotype that activates host anti-tumor immunity [130]. This evidence concerns the gene APOH and neoplasm.