Of the 265 tumors, the expression levels of MTDH in the ER-negative or PR-negative tumor tissue were significantly higher than that in the ER-positive or PR-positive tumors (p = 0.007 and p = 0.014, respectively; Table 1), but no significant correlation was found in those over age 65 (p = 0.656; Table 1), with late-stage tumors (p = 0.092; Table 1), or with HER2-positive tumors (p = 0.379; Table 1). Here, ESR1 is linked to neoplasm.