Radiotherapy of brain cancer is known to induce acute and late pro-inflammatory reactions that involve the production of several cytokines (e.g., TNF-α, IL-1, IL-6, IL-8, IFN-γ) [37], many of which are potent inducers of kinin B1R/B2R expression [38,39]. This evidence concerns the gene BDKRB2 and brain cancer.