In univariate Cox’s regression analysis, the clinicopathological parameters of histological grade, tumor stage (pT1 with/without presence of cis), intravesical therapy and gender, and the molecular parameters KI67, KRT5 and KRT20, were not associated with prognosis (OS, DSS, RFS), and therefore were not included in further multivariate Cox’s regression analysis (data not shown). The gene discussed is MKI67; the disease is neoplasm.