The c-indexes were calculated without each factor in turn as follows: without maximum tumor diameter (c-index = 0.62, 95% CI = 0.51–0.73), without AFP (c-index = 0.63, 95% CI = 0.53–0.73), without age (c-index = 0.64, 95% CI = 0.54–0.74), without PIVKA-II (c-index = 0.65, 95% CI = 0.55–0.77), without portal vein invasion (c-index = 0.66, 95% CI = 0.56–0.76), and without tumor number (c-index = 0.67, 95% CI = 0.57–0.77) (Figure S2). The gene discussed is AFP; the disease is neoplasm.