IFNG and neoplasm: High expression of the IFN-γ signature had an independent influence on MFS in a multivariate analysis adjusted for age, tumor size, axillary nodal status, and histological grade of differentiation both in basal-like breast cancer (HR 3.458, 95% CI 1.154–10.359, p = 0.027) as well as luminal B tumors (HR 2.690, 95% CI 1.416–5.112, p = 0.003; Table 4).