The variety of individual patient prognosis strongly depends on tumor grade (Ohgaki and Kleihues, 2005) as well as genetic features such as isocitrate dehydrogenase (IDH) mutations or O6-methylguanine DNA methyltransferase (MGMT) promotor methylation (Olar et al., 2015, Hegi et al., 2005). The gene discussed is IDH3A; the disease is neoplasm.