To further understand the potential function of circHivep2+ exosomes in the hippocampus of mice with KA‐induced epileptic seizures, we examined Iba1 expression to evaluate microglia activation and the expression of pro‐inflammatory cytokines TNF‐α and IL‐1β, which may be released by activated microglia by Western blotting(Figure 6A‐D) and immunofluorescence (Figure 6E,F). The gene discussed is TNF; the disease is Seizure.