To interrogate whether this dynamic behavior of IFNα-induced antiviral genes is characteristic for Huh7.5 cells and hence potentially determined by the cancer cell context or whether it is conserved in primary hepatocytes, we examined the IFNα-induced expression of the selected IFNα-induced antiviral genes in primary human hepatocytes isolated from a single donor. The gene discussed is IFNA1; the disease is cancer.