SRRM2 is a main component of the spliceosome, and mutation in SRRM2 is associated with the predisposition of papillary thyroid carcinoma [40]. Abnormal expression of CIRBP is involved in the progression and migration of nasopharyngeal carcinoma and bladder cancer [41,42]. The gene discussed is CIRBP; the disease is urinary bladder carcinoma.