When assessing the diagnostic accuracy of Lumipulse CSF Aβ and tau in classifying individuals with clinical AD from cognitively normal controls, Lumipulse ratios of Aβ42/Aβ40, Aβ42/t‐tau, and Aβ42/p‐tau181 were found to have a higher diagnostic accuracy than individual markers.20, 21. This evidence concerns the gene MAPT and Alzheimer disease.