We found that adiponectin concentrations in sarcopenia patients with liver cirrhosis were significantly higher than those in the patients with liver cirrhosis without sarcopenia (32.11 μg/ml [IQR: 23.82, 36.28] vs 24.83 μg/ml [IQR: 18.38–28.42], p = 0.001). This evidence concerns the gene ADIPOQ and cirrhosis of liver.