Transcriptomes from 325 gliomas from the Chinese Glioma Genome Atlas (CGGA) dataset were analysed to investigate the expression of PIEZO1 in gliomas, and we further verified these results by analysing RNA data from The Cancer Genome Atlas (TCGA) network derived from 1032 gliomas and a GSE16011 microarray of 276 cases. This evidence concerns the gene PIEZO1 and glioma.