Upon SEB stimulation, 42/86 (48.8%) genes in HV and 39/86 (45.3%) in septic shock patients were differentially expressed; 12/39 (31%) genes for which expression increased in response to SEB stimulation were specific to septic shock patients (BST2, CD74, HLA-DPA1, HLA-DRA, IRF7, MX1, OAS1, OAS2, RARRES3, SLAMF7, STAT2, TNFSF13B; Fig. 1B). The gene discussed is OAS2; the disease is septic shock.