SGLT1 mRNA expression was comparable among IHD patients with and without CRT, irrespective of T2DM (Fig. 5a), even after adjusting for age, sex, and BMI (estimated marginal means: IHD vs. CRT:IHD: 1.372 ± 0.241 vs. 1.563 ± 0.303, P = 0.642; IHD-T2DM vs. CRT:IHD-T2DM: 1.370 ± 0.287 vs. 1.147 ± 0.265, P = 0.576). Here, SLC5A1 is linked to myocardial ischemia.