Moreover, in agreement with our previous findings with other tumor cells [14–16], elevating SOX2 inhibited the in vitro proliferation of i-SOX2-DU145, i-SOX2-PC3 PCa, i-SOX2-ONS76, and i-SOX2-BE(2)C cells (Fig. 2b, Figure S1B). The gene discussed is SOX2; the disease is posterior cortical atrophy.