We determined 12-genes (BCHE, CCNA1, CYP24A1, DEPTOR, MASP2, MGLL, MYO1A, PODXL2, RAPGEF3, SGK2, TNNI2, ZBTB16) which are highly cancer or lung adenocarcinoma related. This evidence concerns the gene BCHE and lung adenocarcinoma.