AKT3 and lung cancer: When we look at the subnetworks’ graphs, in subnetwork 1 (Fig. 8), the prominent genes are WNT genes which are members of WNT pathway, a major evolutionary conserved signaling pathway playing role in cell differentiation, cell migration and organogenesis during development and highly related to lung cancer; in subnetwork 3 (Fig. 10), the prominent gene is AKT3 which is one of the AKT family members which play role in tumorigenesis and are modulators of several tumors.