It is also the case that some PLHIV are able to naturally control HIV after infection, either spontaneously (“Elite Controllers” and “Exceptional Elite Controllers,” the latter defined as PLHIV with no plasma viremia after at least 10 years of documented infection in the absence of ART, apparently eliminating it through natural immunity)4,5 or after a period of suppressive ART (“Posttreatment Controllers”),17 apparently because they are able to mount effective antiviral CD8+ T cell and/or NK cell responses against HIV. Here, CD8A is linked to infection.